A small medical school research project entitled ‘PPI to strengthen clinical and population health research’ caused me to look at an entirely new field – that of Public and Patient Involvement (PPI). PPI is the development of an active partnership between patients and the public and researchers to work alongside each other not just during trial participation but, at each research step.
Internet research and use of materials supplied by my tutors changed my understanding and appreciation for the field of PPI. Coming across the story surrounding gay rights campaigners and development of early PPI inspired me to investigate how it is used it modern studies. It struck me how despite its importance, PPI often went undiscussed in contemporary studies.
However, one study named PROUD used and reported PPI in an exemplary fashion in order to combat issues and strengthen the trial. PROUD’s PPI improved study design, safety and advertising as well as providing reassurance in difficult times. It also improved recruitment, dissemination of information and made sure that results and future research fields were relevant.
Through PROUD and also my own experiences working with a PPI group I was able to develop an understanding and appreciation for the importance PPI. I write with hope to make my learning available to others.
A research project during my third year at medical school introduced me to PPI. PPI is defined as research carried out with or by members of the public rather than to, about or for them. Historical gay rights activists’ involvement in research catalysed developments in PPI before it was widely recognised. A contemporary study, PROUD, used exemplary PPI contributions to tackle these issues and make the study successful.
My research project was entitled ‘How did PPI contribute towards the PROUD study & what can be learnt from this?’. This letter aims to answer this question but also include my personal reflections on my work and how I developed an understanding and appreciation for the importance PPI. PubMed and Google were examined, as well as University resources.
SDS siRNA |
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20-abx932743 | Abbexa |
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SDS siRNA |
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20-abx932744 | Abbexa |
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SDS antibody |
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70R-3762 | Fitzgerald | 50 ug | 560.4 EUR |
Description: Rabbit polyclonal SDS antibody raised against the middle region of SDS |
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SDS antibody |
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70R-3627 | Fitzgerald | 50 ug | 560.4 EUR |
Description: Rabbit polyclonal SDS antibody raised against the N terminal of SDS |
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SDS antibody |
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10R-5712 | Fitzgerald | 100 ul | 829.2 EUR |
Description: Mouse monoclonal SDS antibody |
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SDS antibody |
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10R-5718 | Fitzgerald | 100 ul | 829.2 EUR |
Description: Mouse monoclonal SDS antibody |
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SDS antibody |
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10R-5720 | Fitzgerald | 100 ul | 829.2 EUR |
Description: Mouse monoclonal SDS antibody |
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SDS siRNA |
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20-abx904833 | Abbexa |
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10% SDS |
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TG4060 | TopoGen | 1ml | 160.8 EUR |
anti-SDS |
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YF-PA17352 | Abfrontier | 50 ug | 435.6 EUR |
Description: Mouse polyclonal to SDS |
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SDS Solution |
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2102-100 | Biovision | each | 164.4 EUR |
dAbs scaffold protein anti-Human B5R |
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SDS-L073 | Creative Biolabs | 1 mg | 5395.2 EUR |
Description: Scaffold protein |
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TG-SDS Buffer (Tris-Glycine-SDS) 10X Solution |
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A0030 | Bio Basic | 4L | 113.76 EUR |
TT-SDS (Tris-Tricine-SDS buffer) Premix powder |
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TD8135 | Bio Basic | 1PK, 10L | 91.32 EUR |
TG-SDS, 10X (Tris-Glycine SDS), pH 8.4 |
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UA0030 | Bio Basic | 500ml | 80.88 EUR |
SDS cloning plasmid |
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CSB-CL020926HU-10ug | Cusabio | 10ug | 279.6 EUR |
Description: A cloning plasmid for the SDS gene. |
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SDS Rabbit pAb |
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A12898-100ul | Abclonal | 100 ul | 369.6 EUR |
SDS Rabbit pAb |
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A12898-200ul | Abclonal | 200 ul | 550.8 EUR |
SDS Rabbit pAb |
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A12898-20ul | Abclonal | 20 ul | 219.6 EUR |
SDS Rabbit pAb |
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A12898-50ul | Abclonal | 50 ul | 267.6 EUR |
SDS Blocking Peptide |
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33R-4446 | Fitzgerald | 100 ug | 216 EUR |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of SDS antibody, catalog no. 70R-3762 |
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SDS Blocking Peptide |
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33R-1011 | Fitzgerald | 100 ug | 216 EUR |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of DISC1 antibody, catalog no. 70R-2399 |
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SDS Polyclonal Antibody |
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27842-100ul | SAB | 100ul | 302.4 EUR |
SDS Polyclonal Antibody |
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27842-50ul | SAB | 50ul | 224.4 EUR |
10% SDS Solution |
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S0792-050 | GenDepot | 500ml | 111.6 EUR |
10% SDS Solution |
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S0792-100 | GenDepot | 2X500ml | 146.4 EUR |
20% SDS Solution |
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S0793-050 | GenDepot | 500ml | 144 EUR |
20% SDS Solution |
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S0793-100 | GenDepot | 2X500ml | 199.2 EUR |
SurfactAway™ SDS |
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SA645-30 | Biotech Support Group | 30 mL | 454.8 EUR |
SurfactAway™ SDS |
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SA646-250 | Biotech Support Group | 250 mL | 1666.8 EUR |
Anti-SDS (1A9) |
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YF-MA17551 | Abfrontier | 100 ug | 435.6 EUR |
Description: Mouse monoclonal to SDS |
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Anti-SDS antibody |
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STJ114764 | St John's Laboratory | 100 µl | 332.4 EUR |
Description: This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. |
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100G SDS Ultrapure |
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NAT1072 | Scientific Laboratory Supplies | 100G | 60.42 EUR |
1KG SDS Ultrapure |
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NAT1074 | Scientific Laboratory Supplies | 1KG | 345.42 EUR |
SDS 100 g |
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17131301 | Scientific Laboratory Supplies | EACH | 78.66 EUR |
Residual SDS Detection Kit |
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BSP055 | Bio Basic | 100Assays | 99.67 EUR |
Mouse SDS shRNA Plasmid |
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20-abx981902 | Abbexa |
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Rat SDS shRNA Plasmid |
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20-abx984756 | Abbexa |
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SDS Polyclonal Conjugated Antibody |
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C27842 | SAB | 100ul | 476.4 EUR |
Human SDS shRNA Plasmid |
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20-abx957508 | Abbexa |
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AE-1390 SDS-eliminant |
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2332390 | Atto | 2unit | 361.2 EUR |
Description: SDS r emoval r eagent |
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Bovine SDS ELISA KIT |
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ELI-53006b | Lifescience Market | 96 Tests | 1113.6 EUR |
Human SDS ELISA KIT |
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ELI-29707h | Lifescience Market | 96 Tests | 988.8 EUR |
SDS-PAGE Staining Solution |
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GR103068 | Genorise Scientific | 100 mL | 69.6 EUR |
Mouse Sds ELISA KIT |
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ELI-19881m | Lifescience Market | 96 Tests | 1038 EUR |
SDS ELISA KIT|Human |
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EF005552 | Lifescience Market | 96 Tests | 826.8 EUR |
SDS, 99% Ultra Pure |
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S0800-100 | GenDepot | 1Kg | 375.6 EUR |
SDS, 99% Ultra Pure |
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S0800-250 | GenDepot | 2.5 Kg | 643.2 EUR |
SDS, 99% Ultra Pure |
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S0800-500 | GenDepot | 5 Kg | 1146 EUR |
SDS-Urea-Tris solution |
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SB8896 | Bio Basic | 500ml | 89.23 EUR |
SDS Recombinant Protein (Human) |
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RP027868 | ABM | 100 ug | Ask for price |
SDS Recombinant Protein (Rat) |
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RP227840 | ABM | 100 ug | Ask for price |
SDS Recombinant Protein (Mouse) |
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RP170486 | ABM | 100 ug | Ask for price |
100ML SDS Solution 20% |
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NAT1228 | Scientific Laboratory Supplies | 100ML | 36.82 EUR |
450ML SDS Solution 20% |
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NAT1230 | Scientific Laboratory Supplies | 450ML | 90.06 EUR |
ESSENTIAL SDS FIXING KIT |
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SDSFIXESS | Scientific Laboratory Supplies | EACH | 251.94 EUR |
SDS, 20% Liquid Solution |
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18-234 | Genesee Scientific | 500ml/Unit | 334 EUR |
SDS, 20% Liquid Solution |
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18-234B | Genesee Scientific | 1000ml/Unit | 390 EUR |
NanoGram SDS Assay Kit |
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SDS200 | ProFoldin | 200 assays | 221.78 EUR |
Description: This product includes 20 ml of MPS6 Dye. It is for measurement of 200 samples using 96-well plates. Cuvettes may also be used for measurements. |
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TG-SDS Buffer (Trisbase-Glycine-SDS) 10X Premix powder - 1PK(4L) |
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A0031 | Bio Basic | 4L | 89.23 EUR |
SDS-Blue™ - Coomassie based solution for protein staining in SDS-PAGE |
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04-GSB | Gentaur Genprice |
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Description: SDS-Blue™ is an innovative patented formula, based on Coomassie blue, that comes in a convenient ready to use format for staining proteins in SDS-PAGE (sodium dodecyl sulphate–polyacrylamide gel electrophoresis). The formulation of SDS-Blue™ provides numerous advantages compared to the classic Coomassie staining or to other similar protein stains. SDS-Blue™ provides higher sensitivity, virtually no background and eliminates the need for destaining of the gel due to its high specificity and affinity to bind to protein only. Not only does SDS-Blue™ yield clear and sharp bands, but it also contains no methanol and acetic acid, making it non-hazardous, safe to handle and friendly to the environment when disposed of. Two other advantages that make SDS-Blue™ the better option is that it is not light sensitive and can be stored at ambient temperature for 24 months. And this provides a considerable convenience, especially to laboratories that need and keep big amount of protein staining solutions – no more jammed refrigerators, you can keep SDS-Blue™ wherever it is most convenient for You! |
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SDS-PAGE Gel Preparation Kit |
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abx090646-1Kit | Abbexa | 1 Kit | 243.6 EUR |
SDS-PAGE Gel Preparation Kit |
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AR0138 | BosterBio | 1kit (Enough for 30-50 pieces of gel.) | 115.2 EUR |
Tricine SDS Sample Buffer 2X |
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AR1143 | BosterBio | 6mL (6*1mL) | 78 EUR |
Tris-Glycine SDS Buffer Pack |
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AR1149 | BosterBio | 1L/pack | 66 EUR |
Sds ORF Vector (Rat) (pORF) |
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ORF075948 | ABM | 1.0 ug DNA | 607.2 EUR |
Sds ORF Vector (Mouse) (pORF) |
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ORF056830 | ABM | 1.0 ug DNA | 607.2 EUR |
SDS ORF Vector (Human) (pORF) |
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ORF009290 | ABM | 1.0 ug DNA | 114 EUR |
20% Sodium Dodecyl Sulfate, SDS |
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GR103007 | Genorise Scientific | 200 mL | 141.6 EUR |
5 x SDS Electrophoresis Buffer |
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GR103039 | Genorise Scientific | 1 L | 128.4 EUR |
Sodium Dodecyl Sulfate (SDS) Ultrapure |
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S057-100G | TOKU-E | 100 g | 73.2 EUR |
Sodium Dodecyl Sulfate (SDS) Ultrapure |
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S057-1kG | TOKU-E | 1 kg | 248.4 EUR |
SDS, 10%(w/v) solution |
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SD8118 | Bio Basic | 100ml | 68.35 EUR |
SDS, 20%(w/v) solution |
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SD8119 | Bio Basic | 100ml | 76.7 EUR |
10X Tris-Glycine SDS buffer |
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T8053-050 | GenDepot | 500ml | 102 EUR |
10X Tris-Glycine SDS buffer |
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T8053-100 | GenDepot | 2X500ml | 133.2 EUR |
10X Tris-Glycine SDS buffer |
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T8053-101 | GenDepot | 1L | 118.8 EUR |
10X Tris-Glycine SDS buffer |
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T8053-104 | GenDepot | 4 L | 183.6 EUR |
10X Tris-Glycine SDS buffer |
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T8053-200 | GenDepot | 4X500ml | 163.2 EUR |
10X Tris-Glycine SDS buffer |
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T8053-201 | GenDepot | 2X1L | 162 EUR |
10X Tris-Glycine SDS buffer |
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T8053-401 | GenDepot | 4X1L | 206.4 EUR |
450ML 20X Tris-MOPS SDS |
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NAT1210 | Scientific Laboratory Supplies | 450ML | 80.94 EUR |
450ML 20X Tris-MEPS SDS |
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NAT1212 | Scientific Laboratory Supplies | 450ML | 80.94 EUR |
CONNECTION KIT SDS AFS ESSENTIAL |
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SDSAFSCKT | Scientific Laboratory Supplies | EACH | 216.6 EUR |
KIT DE CONNECTION SDS/INT |
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SDSINTCKT | Scientific Laboratory Supplies | EACH | 85.5 EUR |
Volumetric Sol SDS 0.02M (0.02N) |
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SLS0021 | Scientific Laboratory Supplies | 1L | 255.36 EUR |
Volumetric Sol SDS 0.1M (0.1N) |
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SLS011 | Scientific Laboratory Supplies | 1L | 220.02 EUR |
SDS 200 no Pump 230V |
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TANK50200 | Scientific Laboratory Supplies | EACH | 4870.08 EUR |
SDS 200 with Pump 230V |
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TANK5P200 | Scientific Laboratory Supplies | EACH | 5800.32 EUR |
SDS TANK RIOS VENT FILTER |
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TANKVNT01 | Scientific Laboratory Supplies | EACH | 359.1 EUR |
SDS TANK ELIX VENT FILTER |
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TANKVNT02 | Scientific Laboratory Supplies | EACH | 492.48 EUR |
TG-SDS, 10X pH 8.3 |
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18-237 | Genesee Scientific | 500ml/Unit | 302 EUR |
TG-SDS, 10X pH 8.3 |
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18-237B | Genesee Scientific | 1000ml/Unit | 336 EUR |
3X SDS-PAGE Loading Buffer |
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2108-10 | Biovision | each | 189.6 EUR |
Finegel SDS-PAGE Running Buffer(10X) |
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F1504-050 | GenDepot | 500ml | 181.2 EUR |
Finegel SDS-PAGE Running Buffer(10X) |
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F1504-100 | GenDepot | 2x500ml | 241.2 EUR |
Sodium dodecyl sulphate (SDS) 0.5 g |
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09-2026-50 | Medicago | 0,5 g | 81.6 EUR |
SDS-PAGE Sample Loading Buffer (2x) |
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abx090647-5ml | Abbexa | 5 ml | 210 EUR |
SDS-PAGE Sample Loading Buffer (5x) |
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abx090648-5ml | Abbexa | 5 ml | 226.8 EUR |
SDS-PAGE Sample Loading Buffer (6x) |
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abx090649-5ml | Abbexa | 5 ml | 243.6 EUR |
10x Tris-Glycine-SDS Buffer Solution |
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BA01807 | Bioatlas | 6x100ml | 123.6 EUR |
Description: High purity buffer for various PCR applications. |
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Tris-Glycine SDS Running Buffer Pack |
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AR0139 | BosterBio | 1L/pack (for 5 assyas) | 66 EUR |
SDS-PAGE Resolving Gel Casting Solution |
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P9050-050 | GenDepot | 500ml | 105.6 EUR |
SDS-PAGE Resolving Gel Casting Solution |
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P9050-100 | GenDepot | 2X500ml | 144 EUR |
SDS-PAGE Stacking Gel Casting Solution |
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P9051-010 | GenDepot | 100ml | 96 EUR |
SDS-PAGE Stacking Gel Casting Solution |
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P9051-050 | GenDepot | 500ml | 134.4 EUR |
Sds sgRNA CRISPR Lentivector set (Mouse) |
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K3615401 | ABM | 3 x 1.0 ug | 406.8 EUR |
SDS-PAGE Running Buffer, 10 x |
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GR103017 | Genorise Scientific | 1 L | 106.8 EUR |
4 x Phosphate/SDS Electrophoresis Buffer |
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GR103033 | Genorise Scientific | 1 L | 139.2 EUR |
Sds sgRNA CRISPR Lentivector set (Rat) |
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K6806501 | ABM | 3 x 1.0 ug | 406.8 EUR |
SDS sgRNA CRISPR Lentivector set (Human) |
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K2111301 | ABM | 3 x 1.0 ug | 406.8 EUR |
Human Serine Dehydratase(SDS)ELISA Kit |
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QY-E01421 | Qayee Biotechnology | 96T | 433.2 EUR |
In Vitro SDS-K+ Precipitation Kit |
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TG1010-1 | TopoGen | 100 assays | 550.8 EUR |
In Vitro SDS-K+ Precipitation Kit |
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TG1010-2 | TopoGen | 250 assays | 685.2 EUR |
In Vivo SDS-K+ Precipitation Kit |
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TG1011-1 | TopoGen | 100 assays | 362.4 EUR |
In Vivo SDS-K+ Precipitation Kit |
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TG1011-2 | TopoGen | 250 assays | 496.8 EUR |
CONNECTION KIT SDS ELIX AND RIOS |
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SDSELECKT | Scientific Laboratory Supplies | EACH | 149.34 EUR |
Finegel SDS-PAGE Running Gel Solution(10%) |
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F1500-100 | GenDepot | 2x500ml | 225.6 EUR |
Finegel SDS-PAGE Running Gel Solution(8%) |
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F1501-100 | GenDepot | 2X500ml | 225.6 EUR |
Finegel SDS-PAGE Running Gel Solution(12.5%) |
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F1502-100 | GenDepot | 2X500ml | 225.6 EUR |
Finegel SDS-PAGE Running Gel Solution(15%) |
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F1503-100 | GenDepot | 2X500ml | 225.6 EUR |
100 ML SDS (SODIUM DODECYL SULFATE), 10% |
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46-040-CI | CORNING | 100 mL/pk | 84 EUR |
Description: Media Catalog; Classical Media |
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10x Tris-Glycine-SDS Ready Mixed Powder |
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BA01708 | Bioatlas | 1L | 112.8 EUR |
Description: High purity buffer for various PCR applications. |
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SDS-PAGE Protein Loading Buffer 2X (Reducing) |
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AR0131 | BosterBio | 6mL | 72 EUR |
SDS-PAGE Protein Loading Buffer 5X (Reducing) |
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AR1112 | BosterBio | 3mL | 72 EUR |
Xpert SDS-PAGE Gel Running Buffer(10X) |
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P9000-050 | GenDepot | 500ml | 116.4 EUR |
Xpert SDS-PAGE Gel Running Buffer(10X) |
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P9000-100 | GenDepot | 1L | 165.6 EUR |
Sds sgRNA CRISPR Lentivector (Mouse) (Target 1) |
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K3615402 | ABM | 1.0 ug DNA | 184.8 EUR |
Sds sgRNA CRISPR Lentivector (Mouse) (Target 2) |
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K3615403 | ABM | 1.0 ug DNA | 184.8 EUR |
Sds sgRNA CRISPR Lentivector (Mouse) (Target 3) |
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K3615404 | ABM | 1.0 ug DNA | 184.8 EUR |
Sds sgRNA CRISPR Lentivector (Rat) (Target 1) |
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K6806502 | ABM | 1.0 ug DNA | 184.8 EUR |
Sds sgRNA CRISPR Lentivector (Rat) (Target 2) |
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K6806503 | ABM | 1.0 ug DNA | 184.8 EUR |
Sds sgRNA CRISPR Lentivector (Rat) (Target 3) |
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K6806504 | ABM | 1.0 ug DNA | 184.8 EUR |
SDS sgRNA CRISPR Lentivector (Human) (Target 1) |
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K2111302 | ABM | 1.0 ug DNA | 184.8 EUR |
SDS sgRNA CRISPR Lentivector (Human) (Target 2) |
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K2111303 | ABM | 1.0 ug DNA | 184.8 EUR |
SDS sgRNA CRISPR Lentivector (Human) (Target 3) |
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K2111304 | ABM | 1.0 ug DNA | 184.8 EUR |
SDS Protein Vector (Human) (pPB-C-His) |
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PV037157 | ABM | 500 ng | 394.8 EUR |
SDS Protein Vector (Human) (pPB-N-His) |
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PV037158 | ABM | 500 ng | 394.8 EUR |
SDS Protein Vector (Human) (pPM-C-HA) |
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PV037159 | ABM | 500 ng | 394.8 EUR |
SDS Protein Vector (Human) (pPM-C-His) |
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PV037160 | ABM | 500 ng | 394.8 EUR |
SDS Protein Vector (Mouse) (pPB-C-His) |
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PV227318 | ABM | 500 ng | 723.6 EUR |
SDS Protein Vector (Mouse) (pPB-N-His) |
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PV227319 | ABM | 500 ng | 723.6 EUR |
SDS Protein Vector (Mouse) (pPM-C-HA) |
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PV227320 | ABM | 500 ng | 723.6 EUR |
SDS Protein Vector (Mouse) (pPM-C-His) |
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PV227321 | ABM | 500 ng | 723.6 EUR |
SDS Protein Vector (Rat) (pPB-C-His) |
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PV303790 | ABM | 500 ng | 723.6 EUR |
SDS Protein Vector (Rat) (pPB-N-His) |
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PV303791 | ABM | 500 ng | 723.6 EUR |
SDS Protein Vector (Rat) (pPM-C-HA) |
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PV303792 | ABM | 500 ng | 723.6 EUR |
SDS Protein Vector (Rat) (pPM-C-His) |
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PV303793 | ABM | 500 ng | 723.6 EUR |
Sodium Dodecyl Sulfate (SDS) Dust-Free™ |
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S022-100G | TOKU-E | 100 g | 76.8 EUR |
Sodium Dodecyl Sulfate (SDS) Dust-Free™ |
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S022-1kG | TOKU-E | 1 kg | 242.4 EUR |
Sodium Dodecyl Sulfate (SDS) Dust-Free™ |
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S022-250G | TOKU-E | 250 g | 124.8 EUR |
Sodium Dodecyl Sulfate (SDS) Dust-Free™ |
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S022-500G | TOKU-E | 500 g | 148.8 EUR |
Sds 3'UTR Luciferase Stable Cell Line |
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TU220043 | ABM | 1.0 ml | Ask for price |
Sds 3'UTR GFP Stable Cell Line |
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TU168480 | ABM | 1.0 ml | Ask for price |
Sds 3'UTR GFP Stable Cell Line |
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TU270043 | ABM | 1.0 ml | Ask for price |
Sds 3'UTR Luciferase Stable Cell Line |
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TU118480 | ABM | 1.0 ml | Ask for price |
SDS 3'UTR GFP Stable Cell Line |
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TU072816 | ABM | 1.0 ml | 1672.8 EUR |
SDS 3'UTR Luciferase Stable Cell Line |
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TU022816 | ABM | 1.0 ml | 1672.8 EUR |
Xpro IP Cell Lysis Reagent,SDS Free |
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X3100-010 | GenDepot | 100ml | 208.8 EUR |
Xpro IP Cell Lysis Reagent,SDS Free |
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X3100-050 | GenDepot | 500ml | 380.4 EUR |
1L Tris-Tricine-SDS PAGE Buffer (10X) |
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NAT1214 | Scientific Laboratory Supplies | 1L | 177.84 EUR |
1L Tris-Glycine-SDS PAGE Buffer (10X) |
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NAT1216 | Scientific Laboratory Supplies | 1L | 52.33 EUR |
4L Tris-Glycine-SDS PAGE Buffer (10X) |
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NAT1218 | Scientific Laboratory Supplies | 4L | 101.46 EUR |
ExcelGel SDS Homogeneous 15 pack of 6 |
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80126201 | Scientific Laboratory Supplies | EACH | 640.68 EUR |
PhastGel SDS Buffer Strips pack of 10 |
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17051601 | Scientific Laboratory Supplies | EACH | 116.28 EUR |
SDS TANK RIOS VENT FILTER ß2/PACK |
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TANKVNT21 | Scientific Laboratory Supplies | EACH | 851.58 EUR |
SDS TANK ELIX VENT FILTERß ß2/PACK |
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TANKVNT22 | Scientific Laboratory Supplies | EACH | 1004.34 EUR |
Correspondence with PROUDs lead investigator also informed this letter. It was found that PROUD’s PPI improved study design, safety and advertising as well as providing reassurance in difficult times. It also improved recruitment, dissemination of information and made sure that results and future research fields were relevant. This allows us to understand and appreciate PPI‘s role in research and the provision of healthcare. It is also important to increase discussion and learning around PPI for the future.